On Friday, 188 people died from Covid-19, according to data from the Florida Department of Health.
A total of 10,360 new cases of coronavirus were also recorded as the state struggles to control its spread.
Hospitals across the state are reporting intensive care units at near capacity and are implementing plans to deal with the flood of patients, based on the experience of New York hospitals in March and April.
Approximately a quarter of a million Floridians have tested positive for Covid-19, and the hospitalisation rate is rising rapidly. More than 7,000 people have been admitted, including 1,600 in Miami alone.
Case numbers have been spiking since mid-June with bars, restaurants and beaches being closed down not long after reopening to prevent people gathering in crowds.
Despite the surge in infections, Walt Disney World Resort in Orlando reopened on Saturday, some four months after shutting down. Epcot and Hollywood Studios will reopen on Wednesday.
Temperature checks and other safety measures, as well as changes to dining and queueing for attractions have been implemented.
Similar surges in case numbers of coronavirus have been reported across the south and west of the US, with Arizona, California and Texas particularly badly hit.
New York, once the epicentre of the Covid-19 pandemic in the US, today reported its lowest number of hospitalisations and deaths since St Patrick’s Day in mid-March.